expression data human protein atlas (hpa) Search Results


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Human Protein Atlas hpa kidney expression information14
Hpa Kidney Expression Information14, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Human Protein Atlas hpa data
Biological functional annotation and somatic alteration. ( a ) Waterfall plot of the somatic landscape in the high- and low-risk groups were ranked by mutational frequency. Side bar plot showed the percentage of mutated samples. somatic cells mutation between high-risk and low-risk groups. genes with mutation frequency in top 20 simultaneously displayed in the low-risk group (blue left panel) and high-risk group (red right panel). ( b ) ROC curves measuring the predictive value of the risk-score in the IMvigor210 cohort. The area under the ROC curve was 0.567 for the risk-score. Kaplan-Meier curves for GBM patients with high-risk and low-risk groups in the IMvigor210 cohort. Log-rank test represented an overall P=0.016. CD274 (PD-L1) expressed between low and high-risk groups. The rate of clinical response (Recomplete response/PR: partial response and SD: stable disease/PD: progressive disease) to anti-PD-L1 immunotherapy in high-risk and low-risk groups in the IMvigor210 cohort (two-sided Fisher exact test P=0.095). ( c ) The enriched gene sets in KEGG collection by the low expression of 6-gene signature. the enriched gene sets in KEGG collection by the high expression of 6-gene signature. protein expression <t>of</t> <t>PIK3CA</t> and NF1 in GBM cancer via the Human protein Atlas dataset. Each line representing one particular gene set with unique color, and up-regulated genes located in the left approaching the origin of the coordinates, in contrary to the down-regulated lay on the right of x-axis. Only gene sets with NOM p<0.05 top 5 were considered significant, and shown in the plots. ( d ) protein expression of PIK3CA, NF1, COL5A1, PGPEP1, MSH6 and MFGE8 in GBM cases from the <t>HPA</t> dataset
Hpa Data, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Human Protein Atlas hpa data images
Biological functional annotation and somatic alteration. ( a ) Waterfall plot of the somatic landscape in the high- and low-risk groups were ranked by mutational frequency. Side bar plot showed the percentage of mutated samples. somatic cells mutation between high-risk and low-risk groups. genes with mutation frequency in top 20 simultaneously displayed in the low-risk group (blue left panel) and high-risk group (red right panel). ( b ) ROC curves measuring the predictive value of the risk-score in the IMvigor210 cohort. The area under the ROC curve was 0.567 for the risk-score. Kaplan-Meier curves for GBM patients with high-risk and low-risk groups in the IMvigor210 cohort. Log-rank test represented an overall P=0.016. CD274 (PD-L1) expressed between low and high-risk groups. The rate of clinical response (Recomplete response/PR: partial response and SD: stable disease/PD: progressive disease) to anti-PD-L1 immunotherapy in high-risk and low-risk groups in the IMvigor210 cohort (two-sided Fisher exact test P=0.095). ( c ) The enriched gene sets in KEGG collection by the low expression of 6-gene signature. the enriched gene sets in KEGG collection by the high expression of 6-gene signature. protein expression <t>of</t> <t>PIK3CA</t> and NF1 in GBM cancer via the Human protein Atlas dataset. Each line representing one particular gene set with unique color, and up-regulated genes located in the left approaching the origin of the coordinates, in contrary to the down-regulated lay on the right of x-axis. Only gene sets with NOM p<0.05 top 5 were considered significant, and shown in the plots. ( d ) protein expression of PIK3CA, NF1, COL5A1, PGPEP1, MSH6 and MFGE8 in GBM cases from the <t>HPA</t> dataset
Hpa Data Images, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Biological functional annotation and somatic alteration. ( a ) Waterfall plot of the somatic landscape in the high- and low-risk groups were ranked by mutational frequency. Side bar plot showed the percentage of mutated samples. somatic cells mutation between high-risk and low-risk groups. genes with mutation frequency in top 20 simultaneously displayed in the low-risk group (blue left panel) and high-risk group (red right panel). ( b ) ROC curves measuring the predictive value of the risk-score in the IMvigor210 cohort. The area under the ROC curve was 0.567 for the risk-score. Kaplan-Meier curves for GBM patients with high-risk and low-risk groups in the IMvigor210 cohort. Log-rank test represented an overall P=0.016. CD274 (PD-L1) expressed between low and high-risk groups. The rate of clinical response (Recomplete response/PR: partial response and SD: stable disease/PD: progressive disease) to anti-PD-L1 immunotherapy in high-risk and low-risk groups in the IMvigor210 cohort (two-sided Fisher exact test P=0.095). ( c ) The enriched gene sets in KEGG collection by the low expression of 6-gene signature. the enriched gene sets in KEGG collection by the high expression of 6-gene signature. protein expression of PIK3CA and NF1 in GBM cancer via the Human protein Atlas dataset. Each line representing one particular gene set with unique color, and up-regulated genes located in the left approaching the origin of the coordinates, in contrary to the down-regulated lay on the right of x-axis. Only gene sets with NOM p<0.05 top 5 were considered significant, and shown in the plots. ( d ) protein expression of PIK3CA, NF1, COL5A1, PGPEP1, MSH6 and MFGE8 in GBM cases from the HPA dataset

Journal: Discover Oncology

Article Title: A PIK3CA and NF1 expression-based prognostic signature derived from Mendelian randomization identifies causal immune-regulatory determinants of glioblastoma outcomes

doi: 10.1007/s12672-026-04658-1

Figure Lengend Snippet: Biological functional annotation and somatic alteration. ( a ) Waterfall plot of the somatic landscape in the high- and low-risk groups were ranked by mutational frequency. Side bar plot showed the percentage of mutated samples. somatic cells mutation between high-risk and low-risk groups. genes with mutation frequency in top 20 simultaneously displayed in the low-risk group (blue left panel) and high-risk group (red right panel). ( b ) ROC curves measuring the predictive value of the risk-score in the IMvigor210 cohort. The area under the ROC curve was 0.567 for the risk-score. Kaplan-Meier curves for GBM patients with high-risk and low-risk groups in the IMvigor210 cohort. Log-rank test represented an overall P=0.016. CD274 (PD-L1) expressed between low and high-risk groups. The rate of clinical response (Recomplete response/PR: partial response and SD: stable disease/PD: progressive disease) to anti-PD-L1 immunotherapy in high-risk and low-risk groups in the IMvigor210 cohort (two-sided Fisher exact test P=0.095). ( c ) The enriched gene sets in KEGG collection by the low expression of 6-gene signature. the enriched gene sets in KEGG collection by the high expression of 6-gene signature. protein expression of PIK3CA and NF1 in GBM cancer via the Human protein Atlas dataset. Each line representing one particular gene set with unique color, and up-regulated genes located in the left approaching the origin of the coordinates, in contrary to the down-regulated lay on the right of x-axis. Only gene sets with NOM p<0.05 top 5 were considered significant, and shown in the plots. ( d ) protein expression of PIK3CA, NF1, COL5A1, PGPEP1, MSH6 and MFGE8 in GBM cases from the HPA dataset

Article Snippet: Immunohistochemical analysis using Human Protein Atlas (HPA) data confirmed protein expression patterns (Fig. D): PIK3CA: Moderate to strong cytoplasmic staining in 76% of glioma samples (n = 12), consistent with cytosolic/membrane-associated localization.

Techniques: Functional Assay, Mutagenesis, Expressing